Analysis of forearm muscles activity by means of new protocols of multichannel EMG signal recording and processing

Los movimientos voluntarios del cuerpo son controlados por el sistema nervioso central y periférico a través de la contracción de los músculos esqueléticos. La contracción se inicia al liberarse un neurotransmisor sobre la unión neuromuscular, iniciando la propagación de un biopotencial sobre la membrana de las fibras musculares que se desplaza hacia los tendones: el Potencial de Acción de la Unidad Motora (MUAP). La señal electromiográfica de superficie registra la activación continua de dichos potenciales sobre la superficie de la piel y constituye una valiosa herramienta para la investigación, diagnóstico y seguimiento clínico de trastornos musculares, así como para la identificación de la intención movimiento tanto en términos de dirección como de potencia. En el estudio de las enfermedades del sistema neuromuscular es necesario analizar el nivel de actividad, la capacidad de producción de fuerza, la activación muscular conjunta y la predisposición a la fatiga muscular, todos ellos asociados con factores fisiológicos que determinan la resultante contracción mioeléctrica. Además, el uso de matrices de electrodos facilita la investigación de las propiedades periféricas de las unidades motoras activas, las características anatómicas del músculo y los cambios espaciales en su activación, ocasionados por el tipo de tarea motora o la potencia de la misma. El objetivo principal de esta tesis es el diseño e implementación de protocolos experimentales y algoritmos de procesado para extraer información fiable de señales sEMG multicanal en 1 y 2 dimensiones del espacio. Dicha información ha sido interpretada y relacionada con dos patologías específicas de la extremidad superior: Epicondilitis Lateral y Lesión de Esfuerzo Repetitivo. También fue utilizada para identificar la dirección de movimiento y la fuerza asociada a la contracción muscular, cuyos patrones podrían ser de utilidad en aplicaciones donde la señal electromiográfica se utilice para controlar interfaces hombre-máquina como es el caso de terapia física basada en robots, entornos virtuales de rehabilitación o realimentación de la actividad muscular. En resumen, las aportaciones más relevantes de esta tesis son: * La definición de protocolos experimentales orientados al registro de señales sEMG en una región óptima del músculo. * Definición de índices asociados a la co-activación de diferentes músculos * Identificación de señales artefactuadas en registros multicanal * Selección de los canales mas relevantes para el análisis Extracción de un conjunto de características que permita una alta exactitud en la identificación de tareas motoras Los protocolos experimentales y los índices propuestos permitieron establecer que diversos desequilibrios entre músculos extrínsecos del antebrazo podrían desempeñar un papel clave en la fisiopatología de la epicondilitis lateral. Los resultados fueron consistentes en diferentes ejercicios y pueden definir un marco de evaluación para el seguimiento y evaluación de pacientes en programas de rehabilitación motora. Por otra parte, se encontró que las características asociadas con la distribución espacial de los MUAPs mejoran la exactitud en la identificación de la intención de movimiento. Lo que es más, las características extraídas de registros sEMG de alta densidad son más robustas que las extraídas de señales bipolares simples, no sólo por la redundancia de contacto implicada en HD-EMG, sino también porque permite monitorizar las regiones del músculo donde la amplitud de la señal es máxima y que varían con el tipo de ejercicio, permitiendo así una mejor estimación de la activación muscular mediante el análisis de los canales mas relevantes.Voluntary movements are achieved by the contraction of skeletal muscles controlled by the Central and Peripheral Nervous system. The contraction is initiated by the release of a neurotransmitter that promotes a reaction in the walls of the muscular fiber, producing a biopotential known as Motor Unit Action Potential (MUAP) that travels from the neuromuscular junction to the tendons. The surface electromyographic signal records the continuous activation of such potentials over the surface of the skin and constitutes a valuable tool for the diagnosis, monitoring and clinical research of muscular disorders as well as to infer motion intention not only regarding the direction of the movement but also its power. In the study of diseases of the neuromuscular system it is necessary to analyze the level of activity, the capacity of production of strength, the load-sharing between muscles and the probably predisposition to muscular fatigue, all of them associated with physiological factors determining the resultant muscular contraction. Moreover, the use of electrode arrays facilitate the investigation of the peripheral properties of the active Motor Units, the anatomical characteristics of the muscle and the spatial changes induced in their activation of as product of type of movement or power of the contraction.The main objective of this thesis was the design and implementation of experimental protocols, and algorithms to extract information from multichannel sEMG signals in 1 and 2 dimensions of the space. Such information was interpreted and related to pathological events associated to two upper-limb conditions: Lateral Epicondylitis and Repetitive Strain Injury. It was also used to identify the direction of movement and contraction strength which could be useful in applications concerning the use of biofeedback from EMG like in robotic- aided therapies and computer-based rehabilitation training.In summary, the most relevant contributions are:§The definition of experimental protocols intended to find optimal regions for the recording of sEMG signals. §The definition of indices associated to the co- activation of different muscles. §The detection of low-quality signals in multichannel sEMG recordings.§ The selection of the most relevant EMG channels for the analysis§The extraction of a set of features that led to high classification accuracy in the identification of tasks.The experimental protocols and the proposed indices allowed establishing that imbalances between extrinsic muscles of the forearm could play a key role in the pathophysiology of lateral epicondylalgia. Results were consistent in different types of motor task and may define an assessment framework for the monitoring and evaluation of patients during rehabilitation programs.On the other hand, it was found that features associated with the spatial distribution of the MUAPs improve the accuracy of the identification of motion intention. What is more, features extracted from high density EMG recordings are more robust not only because it implies contact redundancy but also because it allows the tracking of (task changing) skin surface areas where EMG amplitude is maximal and a better estimation of muscle activity by the proper selection of the most significant channels

Spatial distribution of HD-EMG improves identification of task and force in patients with incomplete spinal cord injury

Background: Recent studies show that spatial distribution of High Density surface EMG maps (HD-EMG) improves the identification of tasks and their corresponding contraction levels. However, in patients with incomplete spinal cord injury (iSCI), some nerves that control muscles are damaged, leaving some muscle parts without an innervation. Therefore, HD-EMG maps in patients with iSCI are affected by the injury and they can be different for every patient. The objective of this study is to investigate the spatial distribution of intensity in HD-EMG recordings to distinguish co-activation patterns for different tasks and effort levels in patients with iSCI. These patterns are evaluated to be used for extraction of motion intention.; Method: HD-EMG was recorded in patients during four isometric tasks of the forearm at three different effort levels. A linear discriminant classifier based on intensity and spatial features of HD-EMG maps of five upper-limb muscles was used to identify the attempted tasks. Task and force identification were evaluated for each patient individually, and the reliability of the identification was tested with respect to muscle fatigue and time interval between training and identification. Results: Three feature sets were analyzed in the identification: 1) intensity of the HD-EMG map, 2) intensity and center of gravity of HD-EMG maps and 3) intensity of a single differential EMG channel (gold standard).; Results show that the combination of intensity and spatial features in classification identifies tasks and effort levels properly (Acc = 98.8 %; S = 92.5 %; P = 93.2 %; SP = 99.4 %) and outperforms significantly the other two feature sets (p < 0.05).; Conclusion: In spite of the limited motor functionality, a specific co-activation pattern for each patient exists for both intensity, and spatial distribution of myoelectric activity. The spatial distribution is less sensitive than intensity to myoelectric changes that occur due to fatigue, and other time-dependent influences.Peer ReviewedPostprint (published version

Prediction of isometric motor tasks and effort levels based on high-density EMG in patients with incomplete spinal cord injury

Objective. The development of modern assistive and rehabilitation devices requires reliable and easy-to-use methods to extract neural information for control of devices. Group-specific pattern recognition identifiers are influenced by inter-subject variability. Based on high-density EMG (HD-EMG) maps, our research group has already shown that inter-subject muscle activation patterns exist in a population of healthy subjects. The aim of this paper is to analyze muscle activation patterns associated with four tasks (flexion/extension of the elbow, and supination/pronation of the forearm) at three different effort levels in a group of patients with incomplete Spinal Cord Injury (iSCI). Approach. Muscle activation patterns were evaluated by the automatic identification of these four isometric tasks along with the identification of levels of voluntary contractions. Two types of classifiers were considered in the identification: linear discriminant analysis and support vector machine. Main results. Results show that performance of classification increases when combining features extracted from intensity and spatial information of HD-EMG maps (accuracy = 97.5%). Moreover, when compared to a population with injuries at different levels, a lower variability between activation maps was obtained within a group of patients with similar injury suggesting stronger task-specific and effort-level-specific co-activation patterns, which enable better prediction results. Significance. Despite the challenge of identifying both the four tasks and the three effort levels in patients with iSCI, promising results were obtained which support the use of HD-EMG features for providing useful information regarding motion and force intentionPeer ReviewedPostprint (author's final draft

Electromiografía de superficie multicanal como herramienta no invasiva en la rehabilitación neuromuscular

La señal EMG de superficie permite analizar cuantitativamente los cambios fisiológicos ocasionados por diferentes patologías ya sea sobre la Médula espinal, las Motoneuronas, la unión neuromuscular o los músculos propiamente dichos. Por tratarse de una técnica no invasiva, facilita el proceso de diagnóstico y monitorización de dichas enfermedades. Por otra parte, la EMG multicanal permite estudiar directamente los determinantes fisiológicos de la fatiga muscular, relacionados con cambios a nivel celular que ocasionan variaciones en la conducción de los potenciales de acción sobre las fibras musculares. En este estudio se introducen los mecanismos de la contracción muscular, su relación con la señal EMG y se presentan dos ejemplos de aplicación en el estudio de patologías de la extremidad superior.Postprint (published version

Identificación de tareas isométricas y dinámicas del miembro superior basada en EMG de alta densidad

La identificación de tareas y estimación del movimiento voluntario basados en electromiografía (EMG) constituyen un problema conocido que involucra diferentes áreas en sistemas expertos, particularmente la de reconocimiento de patrones, con muchas aplicaciones posibles en dispositivos de asistencia y rehabilitación. La información que proporciona puede resultar útil para el control de exoesqueletos o brazos robóticos utilizados en terapias activas. La tecnología emergente de electromiografía de alta densidad (HD-EMG) abre nuevas posibilidades para extraer información neural y ya ha sido reportado que la distribución espacial de mapas de intensidad HD-EMG es una característica valiosa en la identificación de tareas isométricas (contracciones que no producen cambio en la longitud del músculo). Este estudio explora la utilización de la distribución espacial de la actividad mioeléctrica y lleva a cabo identificación de tareas durante ejercicios dinámicos a diferentes velocidades que son mucho más cercanos a los que se utilizan habitualmente en las terapias de rehabilitación. Con este objetivo, se registraron señales HD-EMG en un grupo de sujetos sanos durante la realización de un conjunto de tareas isométricas y dinámicas del miembro superior. Los resultados indican que la distribución espacial es una característica muy útil en la identificación, no solo de contracciones isométricas sino también de contracciones dinámicas, mejorando la eficiencia y naturalidad del control de dispositivos de rehabilitación para que se adapte mejor al usuario.Identification of tasks and estimation of volitional movement based on electromyography (EMG) constitute a known problem that involves different areas in the field of expert systems and particularly pattern recognition, with many possible applications in assistive and rehabilitation devices. The obtained information can be very useful to control exoskeletons or robots used in active rehabilitation processes. The emerging technology of high-density electromyography (HD-EMG) opens up new possibilities to extract neural information, and it has already been reported that the spatial distribution of HD-EMG intensity maps is a valuable feature in the identification of isometric tasks. This study explores the use of the spatial distribution of myoelectric activity and carries out a task identification during dynamic exercises at different velocities which are much closer to the ones commonly used during therapy. To this end, HD-EMG signals were recorded in a group of healthy subjects while performing a set of isometric and dynamic upper limb tasks. The results show that spatial distribution is a very useful feature in the identification not only of isometric contractions but also of dynamic contractions, so it can be very useful to improve the control of rehabilitation devices, making it more natural and permitting to adapt better to the user

Inductively coupled probe for the measurement of partial discharges

Partial discharges are a transient phenomena whose measurement is remarkably important for electrical equipment diagnosis and maintenance. These discharges appear in the measurement circuit as very narrow current pulses of some nanoseconds. Therefore, discharge pulse detection is a particularly difficult problem, especially because they are superposed on the high voltage waveforms that cause them. In this paper, we present an inductively coupled probe able to measure this physical phenomenon by means of a very simple and inexpensive device that can be installed. in the equipment under test. After modeling the probe, its response will be compared to that of commercial devices using both calibrated discharges and partial discharges occurring at real powerThis research has been supported by the Spanish Science and Technology Ministry DPI 2006-15625-C03-02

A novel spatial feature for the identification of motor tasks using high-density electromyography

Estimation of neuromuscular intention using electromyography (EMG) and pattern recognition is still an open problem. One of the reasons is that the pattern-recognition approach is greatly influenced by temporal changes in electromyograms caused by the variations in the conductivity of the skin and/or electrodes, or physiological changes such as muscle fatigue. This paper proposes novel features for task identification extracted from the high-density electromyographic signal (HD-EMG) by applying the mean shift channel selection algorithm evaluated using a simple and fast classifier-linear discriminant analysis. HD-EMG was recorded from eight subjects during four upper-limb isometric motor tasks (flexion/extension, supination/pronation of the forearm) at three different levels of effort. Task and effort level identification showed very high classification rates in all cases. This new feature performed remarkably well particularly in the identification at very low effort levels. This could be a step towards the natural control in everyday applications where a subject could use low levels of effort to achieve motor tasks. Furthermore, it ensures reliable identification even in the presence of myoelectric fatigue and showed robustness to temporal changes in EMG, which could make it suitable in long-term applications

El hombre de las cavernas? : Desmantelando un tópico

Jornadas de Jóvenes en Investigación Arqueológica, JIA (3as : 5-7 de mayo 2010 : Universitat Autònoma de Barcelona). Sesión 10. Los tópicos en arqueología. Reflexiones en torno a la mitificación del pasado.Entre los distintos tópicos existentes en el ideario colectivo se encuentra el del "hombre de las cavernas", el cual presupone que la cueva fue el lugar de habitación exclusivo de los grupos de cazadores recolectores del paleolítico. Este artículo está enfocado para rastrear el origen y consolidación de este mito para, en último término, y mediante la evidencia arqueológica, someterlo a un juicio crítico que concluya en su desmantelamiento.The "cave man" is one of the topics that exist nowadays in our colective ideology. It asume that the cave was the exclusive habitat site of the harvester-hunters groups of the paleolithic time. This article is approached in order to look up the origin and consolidation of this myth to, through the archaelogical evidence, submit it to a critical judgement which deny that idea.Entre els diferents tòpics existents en l'ideari col·lectiu es troba el de "l'home de les cavernes", el qual pressuposa que la cova fou el lloc d'habitatge exclusiu dels grups de caçadors recol·lectors del paleolític. Aquest article està enfocat per a rastrejar l'origen I consolidació d'aquest mite per, en ultimo terme, I mitjançant l'evidència arqueològica, sotmetre'l a un judici crític que conclogui en el seu desmantellament

Coordinated management of low voltage power networks with photovoltaic energy sources

Over the last decades, active power networks have reached great attention due to the incorporation of distributed energy resources into low voltage power systems. In this paper, a decentralized energy management strategy is proposed as an efficient way to minimize both active power losses and voltage profile deviation of an distribution power network with photovoltaic solar farms, and also at the same time, aims to improve the reliability and the security of supply. The coordinated energy management concept relies on a two-step optimization approach based on genetic algorithms (GA) and MINLP, in which a multi-objective function is used which takes into account reliability and operational technical constraints in its formulation. The suitability of the proposed methodology is tested on an existing low voltage power system, in which two aspects are considered: firstly, determining the optimal allocation of PV units and secondly, establishing the optimal reschedule of the active power of the generation units partic ipating in the energy mix and minimizing both the real power losses and voltage deviation of the entire power system.This work has been partly funded by the European Union seventh framework program FP7-SMARTCITIES-2013 under grant agreement 608860 IDE4L – Ideal grid for all

Detection of multiple innervation zones from multi-channel surface EMG recordings with low signal-to-noise ratio using graph-cut segmentation

Knowledge of the location of muscle Innervation Zones (IZs) is important in many applications, e.g. for minimizing the quantity of injected botulinum toxin for the treatment of spasticity or for deciding on the type of episiotomy during child delivery. Surface EMG (sEMG) can be noninvasively recorded to assess physiological and morphological characteristics of contracting muscles. However, it is not often possible to record signals of high quality. Moreover, muscles could have multiple IZs, which should all be identified. We designed a fully-automatic algorithm based on the enhanced image Graph-Cut segmentation and morphological image processing methods to identify up to five IZs in 60-ms intervals of very-low to moderate quality sEMG signal detected with multi-channel electrodes (20 bipolar channels with Inter Electrode Distance (IED) of 5 mm). An anisotropic multilayered cylinder model was used to simulate 750 sEMG signals with signal-to-noise ratio ranging from -5 to 15 dB (using Gaussian noise) and in each 60-ms signal frame, 1 to 5 IZs were included. The micro- and macro- averaged performance indices were then reported for the proposed IZ detection algorithm. In the micro-averaging procedure, the number of True Positives, False Positives and False Negatives in each frame were summed up to generate cumulative measures. In the macro-averaging, on the other hand, precision and recall were calculated for each frame and their averages are used to determine F1-score. Overall, the micro (macro)-averaged sensitivity, precision and F1-score of the algorithm for IZ channel identification were 82.7% (87.5%), 92.9% (94.0%) and 87.5% (90.6%), respectively. For the correctly identified IZ locations, the average bias error was of 0.02±0.10 IED ratio. Also, the average absolute conduction velocity estimation error was 0.41±0.40 m/s for such frames. The sensitivity analysis including increasing IED and reducing interpolation coefficient for time samples was performed. Meanwhile, the effect of adding power-line interference and using other image interpolation methods on the deterioration of the performance of the proposed algorithm was investigated. The average running time of the proposed algorithm on each 60-ms sEMG frame was 25.5±8.9 (s) on an Intel dual-core 1.83 GHz CPU with 2 GB of RAM. The proposed algorithm correctly and precisely identified multiple IZs in each signal epoch in a wide range of signal quality and is thus a promising new offline tool for electrophysiological studies.The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the Seventh Framework Programme of the European Union (FP7/2007-2013) under REA grant agreement no. 600388 (TECNIOspring programme), from the Agency for Business Competitiveness of the Government of Catalonia, ACCIÓ, and from Spanish Ministry of Economy and Competitiveness- Spain (project DPI2014-59049-R).Peer ReviewedPostprint (published version